原文：Published online before print February 6, 2006, 10.1073/pnas.0511034103 PNAS | February 14, 2006 | vol. 103 | no. 7 | 2252-2256 A transgenic approach for RNA interference-based genetic screening in mice Shaohua Peng, J. Philippe York, and Pumin Zhang附：Assistant Professor, Department of Molecular Physiology & BiophysicsPh.D., University of Wisconsin-MadisonSelected Publications:Tetzlaff MT, et al. (2004). Defective cardiovascular development and elevated cyclin E and Notch proteins in mice lacking the Fbw7 F-box protein. Proc Natl Acad Sci USA. 101:3338-45. Delgado I, et al. (2003). Dynamic gene expression during the onset of myoblast differentiation in vitro. Genomics. 82:109-21. Zhang P, Liu M, Elledge S. (2002). Towards genetic genome projects: genomic library screening and gene targeting vector construction in a single step. Nature Genet. 30:31-9. Mei J, Huan, X, Zhang P. (2001). Securin is not required for cellular viability, but is required for normal growth of mouse embryonic fibroblasts. Curr. Biol. 11:1197-201. Zhang P. (1999) Cell cycle control and development: redundant roles of cell cycle regulators. Curr. Opin. Cell Biol. 11:655-62. Zhang P, Wong C, Liu D, Finegold M, Harper JW, Elledge SJ. (1999). p21CIP1 and p57KIP2 control the development of skeletal muscle at myogenin step. Genes Dev. 13:213-24. Zhang P, Wong C, DePinho RA, Harper JW, Elledge SJ. (1998). Cooperation between the Cdk inhibitors p27KIP1 and p57KIP2 in the control of tissue growth and development. Genes Dev. 12:3162-7. Zhang P, et al. (1997). Altered cellular differentiation and proliferation in mice lacking p57 indicates a role in Beckwith-Wiedemann Syndrome. Nature. 387:151-8.
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